Nectin-4 regulates cellular senescence-associated enlargement of cell size

Abstract Cellular senescence is defined as irreversible growth arrest induced by various stress, such as DNA damage and oxidative stress. Senescent cells exhibit various characteristic morphological changes including enlarged morphology. In our recent study, we identified Nectin-4 to be upregulated...

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Bibliographic Details
Main Authors: Ryoko Katasho, Taiki Nagano, Tetsushi Iwasaki, Shinji Kamada
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48890-z