Mfsd2a (Major Facilitator Superfamily Domain Containing 2a) Attenuates Intracerebral Hemorrhage–Induced Blood–Brain Barrier Disruption by Inhibiting Vesicular Transcytosis

Mfsd2a (Major Facilitator Superfamily Domain Containing 2a) Attenuates Intracerebral Hemorrhage–Induced Blood–Brain Barrier Disruption by Inhibiting Vesicular Transcytosis

BackgroundBlood–brain barrier (BBB) disruption aggravates brain injury induced by intracerebral hemorrhage (ICH); however, the mechanisms of BBB damage caused by ICH remain elusive. Mfsd2a (major facilitator superfamily domain containing 2a) has been known to play an essential role in BBB formation...

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Bibliographic Details
Main Authors: Yuan‐Rui Yang, Xiao‐Yi Xiong, Juan Liu, Li‐Rong Wu, Qi Zhong, Kai Zhou, Zhao‐You Meng, Liang Liu, Fa‐Xiang Wang, Qiu‐Wen Gong, Mao‐Fan Liao, Chun‐Mei Duan, Jie Li, Mei‐Hua Yang, Qin Zhang, Chang‐Xiong Gong, Qing‐Wu Yang
Format: Article
Language:English
Published: Wiley 2017-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
blood–brain barrier
intracerebral hemorrhage
Mfsd2a
vesicular transcytosis
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.005811

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.117.005811

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