FOXO3 and PTEN expression in the ovary of girls with extra-gonadal cancer with or without chemotherapy treatment prior to cryopreservation

FOXO3 and PTEN expression in the ovary of girls with extra-gonadal cancer with or without chemotherapy treatment prior to cryopreservation

Abstract Background FOXO3/pFOXO3 and PTEN expression is known to regulate the dormancy/activation of ovarian primordial follicles. How chemotherapy could influence the expression of FOXO3 and PTEN in pre- and post-menarcheal girls with extra-gonadal cancer remains unexplored. Methods Ovarian samples...

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Bibliographic Details
Main Authors: María Itatí Albamonte, Lara Y. Calabró, Mirta S. Albamonte, Alfredo D. Vitullo
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Women's Health
Subjects:
FOXO3
PTEN
Cryopreservation
Pre-menarcheal ovary
Post-menarcheal ovary
Ovarian reserve
Online Access:https://doi.org/10.1186/s12905-023-02648-x

Internet

https://doi.org/10.1186/s12905-023-02648-x

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