DIRAS3 enhances RNF19B-mediated RAC1 ubiquitination and degradation in non-small-cell lung cancer cells

DIRAS3 enhances RNF19B-mediated RAC1 ubiquitination and degradation in non-small-cell lung cancer cells

Summary: Distant metastasis remains the leading cause of high mortality in patients with non-small-cell lung cancer (NSCLC). DIRAS3 is a candidate tumor suppressor protein that is decreased in various tumors. However, the regulatory mechanism of DIRAS3 on metastasis of NSCLC remains unclear. Here, w...

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Bibliographic Details
Main Authors: Yingying Wang, Minli Wei, Min Su, Zhiyuan Du, Jiaxi Dong, Yu Zhang, Yingdi Wu, Xiaopeng Li, Ling Su, Xiangguo Liu
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Molecular biology
Cell biology
Biotechnology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223012348

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http://www.sciencedirect.com/science/article/pii/S2589004223012348

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