Biological Pathways in Adolescent Aortic Stiffness

Biological Pathways in Adolescent Aortic Stiffness

Background Aortic stiffening begins in youth and antedates future hypertension. In adults, excess weight, systemic inflammation, dyslipidemia, insulin resistance, neurohormonal activation, and altered adipokines are implicated in the pathogenesis of increased aortic stiffness. In adolescents, we ass...

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Bibliographic Details
Main Authors: Justin P. Zachariah, Yunfei Wang, Jane W. Newburger, Sarah D. deFerranti, Gary F Mitchell, Ramachandran S. Vasan
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
adipokines
arterial stiffness
cholesterol
hypertension
inflammation
obesity
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.018419

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.018419

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