Examining interactions between polygenic scores and interpersonal trauma exposure on alcohol consumption and use disorder in an ancestrally diverse college cohort

Examining interactions between polygenic scores and interpersonal trauma exposure on alcohol consumption and use disorder in an ancestrally diverse college cohort

Introduction: Genetic factors impact alcohol consumption and use disorder (AUD), with large-scale genome-wide association studies (GWAS) identifying numerous associated variants. Aggregate genetic methods in combination with important environmental factors (e.g., interpersonal trauma [IPT]) can be a...

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Bibliographic Details
Main Authors: Christina M. Sheerin, Rowan K. O’Hara-Payne, Eva E. Lancaster, Hailie Suarez-Rivas, Spit for Science Working Group, Chris Chatzinakos, Elizabeth C. Prom-Wormley, Roseann E. Peterson, Fazil Aliev, Amy E. Adkins, Ananda Amstadter, Thomas Bannard, Peter Barr, Erin C. Berenz, Katie Bountress, Holly Byers, A. Christian Pais, Erin Caraway, James S. Clifford, Megan Cooke, Karen Chartier, Seung B. Cho, Elizabeth Do, Danielle M. Dick, Alexis C. Edwards, Renolda Gelzinis, Neeru Goyal, Sage Hawn, Laura M. Hack, Lisa J. Halberstadt, Sally Kuo, Jacquelyn L. Meyers, Emily Lasko, Jennifer Lend, Emily Lilley, Mackenzie Lind, Elizabeth Long, Alexandra Martelli, Arden Moscati, Anne Morris, Ashlee Moore, Kerry Mitchell, Aashir Nasim, Zoe Neale, Jill Opalesky, Cassie Overstreet, Kimberly Pedersen, Tarah Raldiris, Brien Riley, Jessica Salvatore, Jeanne Savage, David Sosnowski, Rebecca Smith, Jinni Su, Cuie Sun, Nathaniel Thomas, Chloe Walker, Marcie Walsh, Bradley T. Webb, Teresa Willoughby, Brandon Wormley, Madison Woodroof, Jia Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Genetics
Subjects:
alcohol consumption
alcohol use disorder (AUD)
interpersonal trauma
polygenic score (PGS)
college and university students
physical assault
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1274381/full

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https://www.frontiersin.org/articles/10.3389/fgene.2023.1274381/full

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