Focusing on the hypoxia-inducible factor pathway: role, regulation, and therapy for osteoarthritis

Abstract Osteoarthritis (OA) is a common chronic disabling disease that affects hundreds of millions of people around the world. The most important pathological feature is the rupture and loss of articular cartilage, and the characteristics of avascular joint tissues lead to limited repair ability....

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Bibliographic Details
Main Authors: Hanhan Guo, Jianghong Huang, Yujie Liang, Daping Wang, Huawei Zhang
Format: Article
Language:English
Published: BMC 2022-12-01
Series:European Journal of Medical Research
Online Access:https://doi.org/10.1186/s40001-022-00926-2