The Use of 4-(3,4-Dichlorophenyl)-4-Oxo-2-(4-Antipyrinyl)-Butanoic Acid in the Preparation of Some New Heterocyclic Compounds With Expected Biological Activity

The Use of 4-(3,4-Dichlorophenyl)-4-Oxo-2-(4-Antipyrinyl)-Butanoic Acid in the Preparation of Some New Heterocyclic Compounds With Expected Biological Activity

Reaction of 4-oxo-4-(3,4-dichlorophenyl)-2-butenoic acid (1) with antipyrin (2) gave the corresponding butanoic acid 3. Reaction of 3 with hydrazines gave the pyridazinone derivatives 5a,b. Compounds 5a,b were used to prepare the corresponding dithio derivatives. Reaction of 5a with POCl3 unexpected...

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Bibliographic Details
Main Authors: M. Shafik, W. E. Boraie, G. A. Meligi, A. A. Hamed, G. H. Sayed
Format: Article
Language:English
Published: MDPI AG 2003-03-01
Series:Molecules
Subjects:
Substituted pyridazinones
chloropyridazine
substituted thiophenes
Online Access:http://www.mdpi.com/1420-3049/8/3/322/

Internet

http://www.mdpi.com/1420-3049/8/3/322/

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