Antibodies against electronegative LDL inhibit atherosclerosis in LDLr-/- mice

Antibodies against electronegative LDL inhibit atherosclerosis in LDLr-/- mice

In order to determine the effect of antibodies against electronegative low-density lipoprotein LDL(-) on atherogenesis, five groups of LDL low receptor-deficient (LDLr-/-) mice (6 per group) were immunized with the following antibodies (100 µg each): mouse anti-LDL(-) monoclonal IgG2b, rabbit anti-L...

Full description

Bibliographic Details
Main Authors: D.M. Grosso, S. Ferderbar, A.C.B.A. Wanschel, M.H. Krieger, M.L. Higushi, D.S.P. Abdalla
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2008-12-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Minimally modified LDL
Passive immunization
Monoclonal antibody
Atherogenesis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001200007

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001200007

Similar Items