Antifungal activity of dendritic cell lysosomal proteins against Cryptococcus neoformans

Abstract Cryptococcal meningitis is a life-threatening disease among immune compromised individuals that is caused by the opportunistic fungal pathogen Cryptococcus neoformans. Previous studies have shown that the fungus is phagocytosed by dendritic cells (DCs) and trafficked to the lysosome where i...

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Bibliographic Details
Main Authors: Benjamin N. Nelson, Savannah G. Beakley, Sierra Posey, Brittney Conn, Emma Maritz, Janakiram Seshu, Karen L. Wozniak
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92991-6