Microcirculation-driven mitochondrion dysfunction during the progression of experimental sepsis

Abstract Sepsis is accompanied by a less-known mismatch between hemodynamics and mitochondrial respiration. We aimed to characterize the relationship and time dependency of microcirculatory and mitochondrial functions in a rodent model of intraabdominal sepsis. Fecal peritonitis was induced in rats,...

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Bibliographic Details
Main Authors: Roland Fejes, Attila Rutai, László Juhász, Marietta Zita Poles, Andrea Szabó, József Kaszaki, Mihály Boros, Szabolcs Péter Tallósy
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-57855-9