Unsupervised machine learning algorithms identify expected haemorrhage relationships but define unexplained coagulation profiles mapping to thrombotic phenotypes in hereditary haemorrhagic telangiectasia

Abstract Hereditary haemorrhagic telangiectasia (HHT) can result in challenging anaemia and thrombosis phenotypes. Clinical presentations of HHT vary for relatives with identical casual mutations, suggesting other factors may modify severity. To examine objectively, we developed unsupervised machine...

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Bibliographic Details
Main Authors: Ghazel Mukhtar, Claire L. Shovlin
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:eJHaem
Subjects:
Online Access:https://doi.org/10.1002/jha2.746