Cardiac Myosin Binding Protein-C Autoantibodies Are Potential Early Indicators of Cardiac Dysfunction and Patient Outcome in Acute Coronary Syndrome

Cardiac Myosin Binding Protein-C Autoantibodies Are Potential Early Indicators of Cardiac Dysfunction and Patient Outcome in Acute Coronary Syndrome

Summary: The degradation and release of cardiac myosin binding protein-C (cMyBP-C) upon cardiac damage may stimulate an inflammatory response and autoantibody (AAb) production. We determined whether the presence of cMyBP-C-AAbs associated with adverse cardiac function in cardiovascular disease patie...

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Bibliographic Details
Main Authors: Thomas L. Lynch, IVPhD, Diederik W.D. Kuster, PhD, Beverly Gonzalez, ScM, Neelam Balasubramanian, BA, Nandini Nair MD, PhD, Sharlene Day, PhD, Jenna E. Calvino, BA, Yanli Tan, RN, Christoph Liebetrau, MD, Christian Troidl, PhD, Christian W. Hamm, MD, Ahmet Güçlü, MD, Barbara McDonough, RN, Ali J. Marian, MD, Jolanda van der Velden, PhD, Christine E. Seidman, MD, Gordon S. Huggins, MD, Sakthivel Sadayappan, PhD
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:JACC: Basic to Translational Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X17300396

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http://www.sciencedirect.com/science/article/pii/S2452302X17300396

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