Antidiabetic, antioxidant and cytotoxicity activities of ortho- and para-substituted Schiff bases derived from metformin hydrochloride: Validation by molecular docking and in silico ADME studies

Antidiabetic, antioxidant and cytotoxicity activities of ortho- and para-substituted Schiff bases derived from metformin hydrochloride: Validation by molecular docking and in silico ADME studies

Bibliographic Details
Main Authors: Al-Qadsy Inas, Saeed Waseem Sharaf, Al-Odayni Abdel-Basit, Alrabie Ali, Al-Faqeeh Lena Ahmed Saleh, Al-Adhreai Arwa, Al-Owais Ahmad Abdulaziz, Semlali Abdelhabib, Farooqui Mazahar
Format: Article
Language:English
Published: De Gruyter 2023-09-01
Series:Open Chemistry
Subjects:
schiff bases of metformin hydrochloride
2,2-diphenyl-1-picrylhydrazyl (dpph) radical
alpha-amylase
sucrase enzymes
antidiabetic
cytotoxicity assay
docking study
swissadme properties
Online Access:https://doi.org/10.1515/chem-2023-0125

Internet

https://doi.org/10.1515/chem-2023-0125

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