Computational approach to identify potential antileishmanial activity of reported inhibitor, E5700 and two natural alkaloids against Leishmania donovani Squalene Synthase

Leishmania species are the causative agents for Leishmaniasis which is one of the neglected tropical diseases causing 70,000 deaths worldwide each year. Squalene synthase enzyme plays a vital role in sterol metabolism which is essential for Leishmania parasite viability. Therefore squalene synthase...

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Bibliographic Details
Main Authors: Padmika Wadanambi, Emanuele Frontoni
Format: Article
Language:English
Published: Cambridge University Press 2020-01-01
Series:Experimental Results
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2516712X20000374/type/journal_article