Model-based PEEP titration versus standard practice in mechanical ventilation: a randomised controlled trial

Abstract Background Positive end-expiratory pressure (PEEP) at minimum respiratory elastance during mechanical ventilation (MV) in patients with acute respiratory distress syndrome (ARDS) may improve patient care and outcome. The Clinical utilisation of respiratory elastance (CURE) trial is a two-ar...

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Main Authors: Kyeong Tae Kim, Sophie Morton, Sarah Howe, Yeong Shiong Chiew, Jennifer L. Knopp, Paul Docherty, Christopher Pretty, Thomas Desaive, Balazs Benyo, Akos Szlavecz, Knut Moeller, Geoffrey M. Shaw, J. Geoffrey Chase
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-019-4035-7