The fitness cost of antibiotic resistance in Streptococcus pneumoniae: insight from the field.

Laboratory studies have suggested that antibiotic resistance may result in decreased fitness in the bacteria that harbor it. Observational studies have supported this, but due to ethical and practical considerations, it is rare to have experimental control over antibiotic prescription rates.We analy...

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Bibliographic Details
Main Authors: M Cyrus Maher, Wondu Alemayehu, Takele Lakew, Bruce D Gaynor, Sara Haug, Vicky Cevallos, Jeremy D Keenan, Thomas M Lietman, Travis C Porco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3260144?pdf=render