Nuclear-cytoplasmic shuttling of class IIa histone deacetylases regulates somatic cell reprogramming

Class IIa histone deacetylases (HDACs) are a subfamily of HDACs with important functions in development and adult tissue homeostasis. As opposed to other HDACs, they lack catalytic function and bind transcription factors to recruit transcriptional co-regulators, mostly co-repressors such as nuclear...

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Bibliographic Details
Main Authors: Zhiwei Luo, Xiaobing Qing, Christina Benda, Zhijian Huang, Meng Zhang, Yinghua Huang, Hui Zhang, Lulu Wang, Yiwei Lai, Carl Ward, Giacomo Volpe, Xiaofen Zhong, Baoming Qin, Qiang Zhuang, Miguel A. Esteban, Wenjuan Li
Format: Article
Language:English
Published: SpringerOpen 2019-06-01
Series:Cell Regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2045976918300154