TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel

Numata et al examine whether the TRPM7 ion channel plays a role in the activation of volume-sensitive outwardly rectifying Cl− channels (VSOR) using human and chicken cell lines. By genetically-manipulating the expression of TRPM7 and performing electrophysiology, they demonstrate that TRPM7 is an e...

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Bibliographic Details
Main Authors: Tomohiro Numata, Kaori Sato-Numata, Meredith C. Hermosura, Yasuo Mori, Yasunobu Okada
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02127-9