Long non-coding RNA-SNHG7 acts as a target of miR-34a to increase GALNT7 level and regulate PI3K/Akt/mTOR pathway in colorectal cancer progression

Long non-coding RNA-SNHG7 acts as a target of miR-34a to increase GALNT7 level and regulate PI3K/Akt/mTOR pathway in colorectal cancer progression

Abstract Background Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either discrete genetic perturbation or epigenetic dysregulation. The long non-coding RNAs (lncRNAs), emerging as key molecules in human malignancy, has become one of the hot topics in RNA biol...

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Bibliographic Details
Main Authors: Yang Li, Changqian Zeng, Jialei Hu, Yue Pan, Yujia Shan, Bing Liu, Li Jia
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Hematology & Oncology
Subjects:
lncRNA-SNHG7
miR-34a
GALNT7
Progression
Online Access:http://link.springer.com/article/10.1186/s13045-018-0632-2

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http://link.springer.com/article/10.1186/s13045-018-0632-2

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