Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells

Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells

T follicular regulatory cells control the magnitude of the germinal centre response. Here the authors show that these cells display specificity to self as well as foreign antigens, and can arise from Foxp3-negative precursors at early stages of immunization in a PD-L1 dependent manner.

Detaylı Bibliyografya
Asıl Yazarlar: Meryem Aloulou, Edward J. Carr, Mylène Gador, Alexandre Bignon, Roland S. Liblau, Nicolas Fazilleau, Michelle A. Linterman
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Nature Portfolio 2016-01-01
Seri Bilgileri:Nature Communications
Online Erişim:https://doi.org/10.1038/ncomms10579

Internet

https://doi.org/10.1038/ncomms10579

Benzer Materyaller