Prognostic significance of DNMT3a gene expression and reactive nitrogen species in newly diagnosed Egyptian de novo adult acute myeloid leukemia patients

Prognostic significance of DNMT3a gene expression and reactive nitrogen species in newly diagnosed Egyptian de novo adult acute myeloid leukemia patients

Abstract Background DNA methyltransferase 3a (DNMT3a) gene is a frequently dysregulated epigenetic modifier gene involved in the process of carcinogenesis. Also, there is a dichotomous nature of nitric oxide action with the ability to both promote and repress cancers. There is a host of research wor...

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Bibliographic Details
Main Authors: Inas A. Asfour, Hany M. Hegab, Walaa A. El-Salakawy, Mohamed T. Hamza, Dina A. Mansour, Alia M. Saeed
Format: Article
Language:English
Published: SpringerOpen 2020-08-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
AML
APL
DNMT3a
RNS
NO
Online Access:http://link.springer.com/article/10.1186/s43042-020-00066-4

Internet

http://link.springer.com/article/10.1186/s43042-020-00066-4

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