In vivo animal models confirm an increased virulence potential and pathogenicity of the NAP1/RT027/ST01 genotype within the Clostridium difficile MLST Clade 2

In vivo animal models confirm an increased virulence potential and pathogenicity of the NAP1/RT027/ST01 genotype within the Clostridium difficile MLST Clade 2

Abstract Background Based on MLST analyses the global population of C. difficile is distributed in eight clades, of which Clade 2 includes the “hypervirulent” NAP1/RT027/ST01 strain along with various unexplored sequence types (STs). Methods To clarify whether this clinically relevant phenotype is a...

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Bibliographic Details
Main Authors: Josué Orozco-Aguilar, Alejandro Alfaro-Alarcón, Luis Acuña-Amador, Esteban Chaves-Olarte, César Rodríguez, Carlos Quesada-Gómez
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Gut Pathogens
Subjects:
Pathogenicity
Virulence
Clostridium difficile
MLST Clade 2
NAP1/RT027/ST01
Online Access:http://link.springer.com/article/10.1186/s13099-020-00383-4

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http://link.springer.com/article/10.1186/s13099-020-00383-4

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