An iPSC-derived astrocyte model of fragile X syndrome exhibits dysregulated cholesterol homeostasis
Abstract Cholesterol is an essential membrane structural component and steroid hormone precursor, and is involved in numerous signaling processes. Astrocytes regulate brain cholesterol homeostasis and they supply cholesterol to the needs of neurons. ATP-binding cassette transporter A1 (ABCA1) is the...
| Những tác giả chính: | , , , , , , , , , , |
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| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
| Được phát hành: |
Nature Portfolio
2023-07-01
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| Loạt: | Communications Biology |
| Truy cập trực tuyến: | https://doi.org/10.1038/s42003-023-05147-9 |