Integrated analysis reveals that EGR1 promotes epithelial IL33 production in T2 asthma

Integrated analysis reveals that EGR1 promotes epithelial IL33 production in T2 asthma

Abstract Background Airway epithelial cells constitute the first line of defense against external noxious stimuli and play crucial roles in the release of epithelial inflammatory cytokines (IL33, IL25 and TSLP), initiating airway allergic inflammatory diseases such as asthma. IL33 plays critical phy...

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Bibliographic Details
Main Authors: Yan Zhao, Jenil Patel, Jinhua Fan, Xinyang Wang, Lin Chen, Yuanyuan Li, Zhengxiu Luo
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Translational Medicine
Subjects:
Asthma
HDM
Airway epithelial
IL33
EGR1
Online Access:https://doi.org/10.1186/s12967-025-06116-y

Internet

https://doi.org/10.1186/s12967-025-06116-y

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