Impact of Plasmodium falciparum gene deletions on malaria rapid diagnostic test performance

Impact of Plasmodium falciparum gene deletions on malaria rapid diagnostic test performance

Abstract Background Malaria rapid diagnostic tests (RDTs) have greatly improved access to diagnosis in endemic countries. Most RDTs detect Plasmodium falciparum histidine-rich protein 2 (HRP2), but their sensitivity is seriously threatened by the emergence of pfhrp2-deleted parasites. RDTs detecting...

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Bibliographic Details
Main Authors: Michelle L. Gatton, Alisha Chaudhry, Jeff Glenn, Scott Wilson, Yong Ah, Amy Kong, Rosalynn L. Ord, Roxanne R. Rees-Channer, Peter Chiodini, Sandra Incardona, Qin Cheng, Michael Aidoo, Jane Cunningham
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Malaria Journal
Subjects:
Rapid diagnostic tests
Hisidine rich protein 2
HRP2
Gene deletion
Online Access:http://link.springer.com/article/10.1186/s12936-020-03460-w

Internet

http://link.springer.com/article/10.1186/s12936-020-03460-w

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