PML-II regulates ERK and AKT signal activation and IFNα-induced cell death

Abstract Background The requirement of promyelocytic leukaemia protein (PML) in interferon (IFN)-induced cell apoptosis is well-established. However, the exact mechanisms by which the multiple isoforms of PML protein participate in this process remain not well-understood. We previously demonstrated...

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Bibliographic Details
Main Authors: Xueqiong Meng, Yixiang Chen, Salvador Macip, Keith Leppard
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-021-00756-5