Imaging extra-striatal dopamine D2 receptors in a maternal immune activation rat model

Maternal immune activation (MIA) is a risk factor for schizophrenia in the offspring. MIA in pregnant rodents can be induced by injection of synthetic polyriboinosinic-polyribocytidilic acid (Poly I:C), which causes decreased striatal dopamine D2 receptor (D2R) expression and behavioral dysfunction...

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Bibliographic Details
Main Authors: Arata Oh-Nishi, Yuji Nagai, Chie Seki, Tetsuya Suhara, Takafumi Minamimoto, Makoto Higuchi
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Brain, Behavior, & Immunity - Health
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666354622000369