Identification of the Bacterial Biosynthetic Gene Clusters of the Oral Microbiome Illuminates the Unexplored Social Language of Bacteria during Health and Disease

Identification of the Bacterial Biosynthetic Gene Clusters of the Oral Microbiome Illuminates the Unexplored Social Language of Bacteria during Health and Disease

ABSTRACT Small molecules are the primary communication media of the microbial world. Recent bioinformatic studies, exploring the biosynthetic gene clusters (BGCs) which produce many small molecules, have highlighted the incredible biochemical potential of the signaling molecules encoded by the human...

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Bibliographic Details
Main Authors: Gajender Aleti, Jonathon L. Baker, Xiaoyu Tang, Ruth Alvarez, Márcia Dinis, Nini C. Tran, Alexey V. Melnik, Cuncong Zhong, Madeleine Ernst, Pieter C. Dorrestein, Anna Edlund
Format: Article
Language:English
Published: American Society for Microbiology 2019-04-01
Series:mBio
Subjects:
biosynthetic gene clusters
caries
genome mining
oral microbiome
periodontitis
small molecules
Online Access:https://journals.asm.org/doi/10.1128/mBio.00321-19

Internet

https://journals.asm.org/doi/10.1128/mBio.00321-19

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