Potential solutions for manufacture of CAR T cells in cancer immunotherapy

CAR T cell therapy is an effective cancer treatment, but biological and manufacturing hurdles hamper its broad breakthrough. Although the first step towards automated manufacture of CAR cells has been taken, new technologies are needed to enable the treatment of large patient groups.

Bibliographic Details
Main Authors: Ulrich Blache, Georg Popp, Anna Dünkel, Ulrike Koehl, Stephan Fricke
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32866-0