Role of Moesin Phosphorylation in Retinal Pericyte Migration and Detachment Induced by Advanced Glycation Endproducts

Role of Moesin Phosphorylation in Retinal Pericyte Migration and Detachment Induced by Advanced Glycation Endproducts

Proliferative diabetic retinopathy (PDR) involves persistent, uncontrolled formation of premature blood vessels with reduced number of pericytes. Our previous work showed that advanced glycation endproducts (AGEs) induced angiogenesis in human umbilical vein endothelial cells, mouse retina, and aort...

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Bibliographic Details
Main Authors: Shuang-Shuang Zhang, Jia-Qing Hu, Xiao-Hui Liu, Li-Xian Chen, Hong Chen, Xiao-Hua Guo, Qiao-Bing Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Endocrinology
Subjects:
advanced glycation endproducts
rat retinal microvascular pericyte
moesin
CD44
migration
immature neovascularization
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.603450/full

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https://www.frontiersin.org/articles/10.3389/fendo.2020.603450/full

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