Single-cell transcriptome analysis reveals immunosuppressive landscape in overweight and obese colorectal cancer

Single-cell transcriptome analysis reveals immunosuppressive landscape in overweight and obese colorectal cancer

Abstract Background Overweight and obesity are established risk factors for various types of cancers including colorectal cancer (CRC). However the underlying molecular mechanisms remain unclear. An in-depth understanding of the oncologic characteristics of overweight and obese CRC at the single-cel...

Full description

Bibliographic Details
Main Authors: Guozhong Xiao, Yihui Zheng, Huaxian Chen, Minyi Luo, Chaoxin Yang, Donglin Ren, Pengfei Qin, Heng Zhang, Hongcheng Lin
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Translational Medicine
Subjects:
Colorectal cancer
Overweight
Obesity
Obese
Single-cell RNA sequencing
Tumor microenvironment
Online Access:https://doi.org/10.1186/s12967-024-04921-5

Internet

https://doi.org/10.1186/s12967-024-04921-5

Similar Items