Targeting the Plasmodium falciparum’s Thymidylate Monophosphate Kinase for the Identification of Novel Antimalarial Natural Compounds

Recent reports of resistance to artemisinin-based combination drugs necessitate the need to discover novel antimalarial compounds. The present study was aimed at identifying novel antimalarial compounds from natural product libraries using computational methods. Plasmodium falciparum is highly depen...

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Bibliographic Details
Main Authors: Kweku S. Enninful, Samuel K. Kwofie, Mark Tetteh-Tsifoanya, Amanda N. L. Lamptey, Georgina Djameh, Samuel Nyarko, Anita Ghansah, Michael D. Wilson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.868529/full