Multiscale Modeling of the Early CD8 T-Cell Immune Response in Lymph Nodes: An Integrative Study

Multiscale Modeling of the Early CD8 T-Cell Immune Response in Lymph Nodes: An Integrative Study

CD8 T-cells are critical  in controlling infection by intracellular  pathogens. Upon encountering antigen presenting cells, T-cell receptor activation promotes the differentiation of naïve CD8 T-cells into strongly proliferating  activated and effector stages. We propose a 2D-multiscale computation...

Full description

Bibliographic Details
Main Authors: Sotiris A. Prokopiou, Loic Barbarroux, Samuel Bernard, Julien Mafille, Yann Leverrier, Christophe Arpin, Jacqueline Marvel, Olivier Gandrillon, Fabien Crauste
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Computation
Subjects:
multiscale immune modeling
cellular Potts model
CD8 T-cells
APC
Online Access:http://www.mdpi.com/2079-3197/2/4/159

Internet

http://www.mdpi.com/2079-3197/2/4/159

Similar Items