Association between the peripartum maternal and fetal telomere lengths and mitochondrial DNA copy numbers and preeclampsia: a prospective case–control study

Association between the peripartum maternal and fetal telomere lengths and mitochondrial DNA copy numbers and preeclampsia: a prospective case–control study

Abstract Purpose To explore changes in telomere length (TL) and mitochondrial copy number (mtDNA-CN) in preeclampsia (PE) and to evaluate the combined effect of maternal TL and mtDNA-CN on PE risk. Methods A case–control study of 471 subjects (130 PE cases and 341 age frequency matched controls with...

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Bibliographic Details
Main Authors: Ruyi Zhang, Jiangbo Du, Zhendong Xiao, Yuan Jiang, Liang Jin, Qiao Weng
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Pregnancy and Childbirth
Subjects:
Telomere length
Mitochondrial DNA copy number
Preeclampsia
Combined effect
Online Access:https://doi.org/10.1186/s12884-022-04801-0

Internet

https://doi.org/10.1186/s12884-022-04801-0

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