Histamine activates an intracellular Ca2+ signal in normal human lung fibroblast WI-38 cells

Histamine activates an intracellular Ca2+ signal in normal human lung fibroblast WI-38 cells

Histamine is an inflammatory mediator that can be released from mast cells to induce airway remodeling and cause persistent airflow limitation in asthma. In addition to stimulating airway smooth muscle cell constriction and hyperplasia, histamine promotes pulmonary remodeling by inducing fibroblast...

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Bibliographic Details
Main Authors: Roberto Berra-Romani, Ajelet Vargaz-Guadarrama, Josué Sánchez-Gómez, Nayeli Coyotl-Santiago, Efraín Hernández-Arambide, José Everardo Avelino-Cruz, Mario García-Carrasco, Monica Savio, Giorgia Pellavio, Umberto Laforenza, Alfredo Lagunas-Martínez, Francesco Moccia
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
histamine
intracellular Ca2+
lung fibroblasts
WI-38
Ca2+ oscillations
InsP3 receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.991659/full

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https://www.frontiersin.org/articles/10.3389/fcell.2022.991659/full

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