Multifaceted functions of STING in human health and disease: from molecular mechanism to targeted strategy

Abstract Since the discovery of Stimulator of Interferon Genes (STING) as an important pivot for cytosolic DNA sensation and interferon (IFN) induction, intensive efforts have been endeavored to clarify the molecular mechanism of its activation, its physiological function as a ubiquitously expressed...

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Bibliographic Details
Main Authors: Zili Zhang, Haifeng Zhou, Xiaohu Ouyang, Yalan Dong, Alexey Sarapultsev, Shanshan Luo, Desheng Hu
Format: Article
Language:English
Published: Nature Publishing Group 2022-12-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-022-01252-z