Uptake and metabolism of exogenous gangliosides by cultured cells: effect of choleragen on the turnover of GM1.

When added to the culture medium, 3H-labeled GM1 (tritiated predominantly in the terminal galactose residue) was taken up by murine NCTC 2071 and rat glioma C6 cells, both of which are GM1-deficient. Upon incubating the labeled cells in fresh medium, the cell-associated GM1 was metabolized by the ce...

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Bibliographic Details
Main Authors: P H Fishman, R M Bradley, B E Hom, J Moss
Format: Article
Language:English
Published: Elsevier 1983-08-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520379141