A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis

A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis

Abstract Universal stress proteins (USPs) are ubiquitously expressed in bacteria, archaea, and eukaryotes and play a lead role in adaptation to environmental conditions. They enable adaptation of bacterial pathogens to the conditions encountered in the human niche, including hypoxia, oxidative stres...

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Bibliographic Details
Main Authors: Andrew O'Connor, Irene Jurado‐Martín, Margaritha M. Mysior, Anotidaishe L. Manzira, Joanna Drabinska, Jeremy C. Simpson, Mary Lucey, Kirsten Schaffer, Rita Berisio, Siobhán McClean
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:MicrobiologyOpen
Subjects:
adaptation
Burkholderia cenocepacia
chronic infection
cystic fibrosis
intra‐macrophage survival
respiratory infection
Online Access:https://doi.org/10.1002/mbo3.1311

Internet

https://doi.org/10.1002/mbo3.1311

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