Heterogeneous Patterns of Endothelial NF-κB p65 and MAPK c-Jun Activation, Adhesion Molecule Expression, and Leukocyte Recruitment in Lung Microvasculature of Mice with Sepsis

Heterogeneous Patterns of Endothelial NF-κB p65 and MAPK c-Jun Activation, Adhesion Molecule Expression, and Leukocyte Recruitment in Lung Microvasculature of Mice with Sepsis

Background: Sepsis is an uncontrolled systemic inflammatory response to an infection that can result in acute failure of the function of the lung called acute respiratory distress syndrome. Leukocyte recruitment is an important hallmark of acute lung failure in patients with sepsis. Endothelial cell...

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Bibliographic Details
Main Authors: Zhendong Wang, Erna-Zulaikha Dayang, Peter J. Zwiers, Martha L. Hernandez Garcia, Matthijs Luxen, Matijs van Meurs, Jill Moser, Jan A. A. M. Kamps, Grietje Molema
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Series:Biomedicines
Subjects:
polymicrobial abdominal sepsis
lung endothelial cells
NF-κB p65
MAPK c-Jun
endothelial adhesion molecules
leukocytes
Online Access:https://www.mdpi.com/2227-9059/12/8/1672

Internet

https://www.mdpi.com/2227-9059/12/8/1672

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