Lower S-adenosylmethionine levels and DNA hypomethylation of placental growth factor (PlGF) in placental tissue of early-onset preeclampsia-complicated pregnancies.

Lower S-adenosylmethionine levels and DNA hypomethylation of placental growth factor (PlGF) in placental tissue of early-onset preeclampsia-complicated pregnancies.

<h4>Introduction</h4>The pathophysiology of preeclampsia is largely unknown. Serum placental induced growth factor (PlGF) levels are decreased during second trimester pregnancy. Aberrant DNA methylation is suggested to be involved in the etiology of preeclampsia (PE). We hypothesize that...

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Bibliografiska uppgifter
Huvudupphovsmän: Sandra G Heil, Emilie M Herzog, Pieter H Griffioen, Bertrand van Zelst, Sten P Willemsen, Yolanda B de Rijke, Regine P M Steegers-Theunissen, Eric A P Steegers
Materialtyp: Artikel
Språk:English
Publicerad: Public Library of Science (PLoS) 2019-01-01
Serie:PLoS ONE
Länkar:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0226969&type=printable

Internet

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0226969&type=printable

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