Super-Enhancer-Associated Long Non-Coding RNA LINC01485 Promotes Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Regulating MiR-619-5p/RUNX2 Axis

Super-Enhancer-Associated Long Non-Coding RNA LINC01485 Promotes Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Regulating MiR-619-5p/RUNX2 Axis

ObjectiveTo investigate the mechanisms of super-enhancer-associated LINC01485/miR-619-5p/RUNX2 signaling axis involvement in osteogenic differentiation of human bone marrow mesenchymal stem cells (hBMSCs).MethodsOsteogenic differentiation of hBMSCs was induced in vitro. The expression levels of LINC...

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Bibliographic Details
Main Authors: Wenli Gu, Xiao Jiang, Wei Wang, Prabhakar Mujagond, Jingpeng Liu, Zhaoyi Mai, Hai Tang, Simin li, Hui Xiao, Jianjiang Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Endocrinology
Subjects:
LINC01485
miR-619-5p
RUNX2
super-enhancers
bone marrow mesenchymal stem cells
osteogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.846154/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.846154/full

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