Direct differentiation of human pluripotent stem cells into vascular network along with supporting mural cells

During embryonic development, endothelial cells (ECs) undergo vasculogenesis to form a primitive plexus and assemble into networks comprised of mural cell-stabilized vessels with molecularly distinct artery and vein signatures. This organized vasculature is established prior to the initiation of blo...

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Bibliographic Details
Main Authors: Taylor Bertucci, Shravani Kakarla, Max A. Winkelman, Keith Lane, Katherine Stevens, Steven Lotz, Alexander Grath, Daylon James, Sally Temple, Guohao Dai
Format: Article
Language:English
Published: AIP Publishing LLC 2023-09-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0155207