Underexpression of LINC00173 in TCF3/PBX1-Positive Cases Is Associated With Poor Prognosis in Children With B-Cell Precursor Acute Lymphoblastic Leukemia

Underexpression of LINC00173 in TCF3/PBX1-Positive Cases Is Associated With Poor Prognosis in Children With B-Cell Precursor Acute Lymphoblastic Leukemia

BackgroundB-cell precursor acute lymphoblastic leukemia (BCP-ALL) is the most frequent pediatric cancer worldwide. Despite improvements in treatment regimens, approximately 20% of the cases cannot be cured, highlighting the necessity for identifying new biomarkers to improve the current clinical and...

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Main Authors: Didier Ismael May-Hau, Diego Alberto Bárcenas-López, Juan Carlos Núñez-Enríquez, Vilma Carolina Bekker-Méndez, Fredy Omar Beltrán-Anaya, Elva Jiménez-Hernández, Mónica Patricia Ortíz-Maganda, Francisco Xavier Guerra-Castillo, Aurora Medina-Sanson, Janet Flores-Lujano, Jorge Alfonso Martín-Trejo, José Gabriel Peñaloza-González, Martha Margarita Velázquez-Aviña, José Refugio Torres-Nava, Gabriela Alicia Hernández-Echáurregui, Rosa Martha Espinosa-Elizondo, María de Lourdes Gutiérrez-Rivera, Rodrigo Sanchez-Hernandez, María Luisa Pérez-Saldívar, Luz Victoria Flores-Villegas, Laura Elizabeth Merino-Pasaye, David Aldebarán Duarte-Rodríguez, Minerva Mata-Rocha, Omar Alejandro Sepúlveda-Robles, Haydeé Rosas-Vargas, Alfredo Hidalgo-Miranda, Juan Manuel Mejía-Aranguré, Silvia Jiménez-Morales
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
LINC00173
acute lymphoblastic leukemia
TCF3/PBX1
relapse
biomarker
cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.887766/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.887766/full

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