Semaglutide reduces alcohol intake and relapse-like drinking in male and female ratsResearch in context

Semaglutide reduces alcohol intake and relapse-like drinking in male and female ratsResearch in context

Summary: Background: Glucagon-like peptide1 receptor (GLP-1R) agonists have been found to reduce alcohol drinking in rodents and overweight patients with alcohol use disorder (AUD). However, the probability of low semaglutide doses, an agonist with higher potency and affinity for GLP-1R, to attenua...

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Bibliographic Details
Main Authors: Cajsa Aranäs, Christian E. Edvardsson, Olesya T. Shevchouk, Qian Zhang, Sarah Witley, Sebastian Blid Sköldheden, Lindsay Zentveld, Daniel Vallöf, Maximilian Tufvesson-Alm, Elisabet Jerlhag
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:EBioMedicine
Subjects:
GLP-1
Nucleus accumbens
Gut-brain axis
Addition
Dopamine
Reward
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423002074

Internet

http://www.sciencedirect.com/science/article/pii/S2352396423002074

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