Chemopreventive effect of artesunate in 1,2-dimethylhydrazine-induced rat colon carcinogenesis

Chemopreventive effect of artesunate in 1,2-dimethylhydrazine-induced rat colon carcinogenesis

Artesunate (ART) is a semisynthetic derivative of artemisinin. Artemisinin and its derivatives have shown profound cytotoxicity and antitumor activity in addition to antimalarial activity in various studies. As the in vivo chemopreventive efficacy of ART in colon carcinogenesis has not been investig...

Full description

Bibliographic Details
Main Authors: Sazal Patyar, Rakesh Raman Patyar, Bikash Medhi, Krishan Lal Khanduja
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
Aberrant crypt foci
artemisinin
artesunate
apoptosis
cytokines
oxidative stress
tumor necrosis factor-α
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2017;volume=8;issue=3;spage=102;epage=107;aulast=Patyar

Internet

http://www.japtr.org/article.asp?issn=2231-4040;year=2017;volume=8;issue=3;spage=102;epage=107;aulast=Patyar

Similar Items