THE STUDY OF INTESTINAL PERMEABILITY IN VITRO ON A MONOLAYER OF EPITHELIAL CACO-2 CELLS (REVIEW)
This paper is devoted to the application of epithelial monolayer of human colon adenocarcinoma cells — Caco-2 for in vitro permeability evaluation of drugs. Main advantages of this biological model are described. General principles, approaches and methodology of Caco-2 permeability assay are defined...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
2022-12-01
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| Series: | Сеченовский вестник |
| Subjects: | |
| Online Access: | https://www.sechenovmedj.com/jour/article/view/805 |