The germline HLA-A02B62 supertype is associated with a PD-L1-positive tumour immune microenvironment and poor prognosis in stage I lung cancer

The germline HLA-A02B62 supertype is associated with a PD-L1-positive tumour immune microenvironment and poor prognosis in stage I lung cancer

Background: Germline HLA class I molecule supertypes are shown to correlate with response to anti-PD-1 therapy. Here, we investigate the significance of germline HLA-A and HLA-B supertypes in tumour microenvironment of non-small-cell lung cancer. Methods: Totally 278 NSCLC patients were collected re...

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Bibliographic Details
Main Authors: Ruijiang Lin, Xiaohua Chen, Fei Su, Hongbin Wang, Biao Han, Yanhui Chen, Cuixiang Zhang, Minjie Ma
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Heliyon
Subjects:
HLA supertype
PD-L1
Tils
Prognosis
NSCLC
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402306156X

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http://www.sciencedirect.com/science/article/pii/S240584402306156X

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