Sorl1 knockout inhibits expression of brain-derived neurotrophic factor: involvement in the development of late-onset Alzheimer’s disease

Sorl1 knockout inhibits expression of brain-derived neurotrophic factor: involvement in the development of late-onset Alzheimer’s disease

Sortilin-related receptor 1 (SORL1) is a critical gene associated with late-onset Alzheimer’s disease. SORL1 contributes to the development and progression of this neurodegenerative condition by affecting the transport and metabolism of intracellular β-amyloid precursor protein. To better understand...

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Bibliographic Details
Main Authors: Mingri Zhao, Xun Chen, Jiangfeng Liu, Yanjin Feng, Chen Wang, Ting Xu, Wanxi Liu, Xionghao Liu, Mujun Liu, Deren Hou
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Neural Regeneration Research
Subjects:
brain-derived neurotrophic factor; late-onset alzheimer’s disease; n-methyl-d-aspartate receptor; sortilin-related receptor 1; synapse
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=7;spage=1602;epage=1607;aulast=Zhao

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=7;spage=1602;epage=1607;aulast=Zhao

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