Generation of a TRPM8 knockout hESC line (WAe009-A-A) derived from H9 using CRISPR/Cas9

Generation of a TRPM8 knockout hESC line (WAe009-A-A) derived from H9 using CRISPR/Cas9

The transient receptor potential cation channel subfamily M member 8 (TRPM8) is a kind of non-selective cation channel which controls Ca2+ homeostasis. Mutations in TRPM8 were related to dry eye diseases (DED). Here we constructed a TRPM8 knockout cell line WAe009-A-A from the original embryonic ste...

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Bibliographic Details
Main Authors: Jinmeng Bai, Jianchao Zhang, Wanrong Fu, Shuang Li, Xiaoxu Tian, Xiaowei Li, Xiaoyan Zhao, Jianzeng Dong
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506123000260

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http://www.sciencedirect.com/science/article/pii/S1873506123000260

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